IMMUNE SUPPORT + ANTI-AGEING…How does it work?
Taroeva was founded on the belief that placing our customer’s health, safety and wellbeing should be at the heart of everything we do. And this ethos has been our core value in the pursuit of developing bio-active nutrition that can make a difference to our lives today; it's not just about longevity, but feeling healthier as we age.
We don’t want you to just take our “word for it”, we want you to be totally informed before choosing to use our products. In this article we will explain the ins & outs of our product, how it helps you on your wellness journey, along with clinical trials and scientific studies to back all claims.
IMMUNE SUPPORT + ANTI-AGEING
So what is our IMMUNE SUPPORT + ANTI-AGEING blend and why is it improving the biological health of not just Australian’s, but also our customers globally?
We keep our products simple, focusing on the things that actually work. The IMMUNE SUPPORT + ANTI-AGEING blend contains four synergetic ingredients, delivered at an optimal dose that translates into real bio-active benefits. There’s no need to complicate our product by adding multiple low dose ingredients that offer minimal nutritional and wellbeing outcomes
Trans-Resveratrol
Resveratrol has anti-aging, anti-carcinogenic, anti-inflammatory, and anti-oxidant properties that are relevant to chronic diseases and longevity in humans. As a powerful antioxidant, resveratrol acts at the cellular level to boost NAD+ by increasing the activity of a key NAD+ synthesising enzyme involved in DNA protection and repair, also supporting bone health, cardiovascular health, blood glucose levels, healthy cognitive function, and skin youthfulness.
Alpha-tocopherol
Alpha-tocopherol is the most potent fat-soluble antioxidant known in nature. Alpha-tocopherol has been show to support antioxidant functions, cell signaling and gene regulatory functions, along with boosting the immune system and helping to reduce oxidative stress.
Hyaluronic acid
Hyaluronic acid contributes to the increased synthesis of the bodies own Hyaluronic acid and promotes cell proliferation in fibroblasts. This helps address age related symptoms directly, promoting healthy and hydrated skin.
Magnesium Glycinate
Magnesium has a close relationship with the immune system, in both specific and nonspecific immune responses. Magnesium acts as a cofactor for a number of immune system reactions, it functions as a cofactor for antibody-dependent cytolysis, macrophage response, immunoglobulin synthesis, and various other reactions.
Potential Benefits :
Anti-ageing via NAD+ production
Reduction of oxidative stress
Cardiovascular health
Multi-level Immune support
Dermal hydration
Cognitive health
Anti-inflammatory
Joint mobility
Pre-menopause support
Regulating insulin sensitivity
Reduction of LDL and triglyceride levels
Restricts the production of cortisol
What is Trans-Resveratrol (RSV)
In the past decade, the small polyphenol resveratrol has received widespread attention as either a potential therapy or as a preventive agent for numerous diseases. Studies using purified enzymes have suggested that resveratrol has anti-aging, anti-carcinogenic, anti-inflammatory, and anti-oxidant properties that might be relevant to chronic diseases and/or longevity in humans. Although the supporting research in laboratory models is quite substantial, only recently data has emerged to describe the effects of resveratrol supplementation on physiological responses in humans.
The emerging data from human clinical trials confirms what the past decade of in vitro and laboratory animal models have suggested; resveratrol has considerable potential to improve health and prevent chronic disease in humans. Resveratrol has raised attention for being an effective antioxidant and for positively affecting the cells in the body, leading to a number of health benefits. Since its discovery, researchers have published more than 12,000 scientific papers about resveratrol, and over 200 human clinical trials involving this polyphenol have been conducted to date.
We believe the evidence is sufficiently strong to conclude that a single dose of resveratrol is able to induce beneficial physiologic responses, and that either weeks or months of resveratrol supplementation produces physiologic changes that are predictive of improved health, especially in clinical populations with compromised health.
Let’s Take a Closer Look
Resveratrol is a compound that various plants make to fight off bacteria, fungi, and other microbial attackers, or to withstand drought or lack of nutrients. It has been found in red and purple grapes, blueberries, cranberries, mulberries, lingonberries, peanuts, and Resveratrol is also abundant in the roots of Japanese knotweed.
Scientific evidence suggests that it does the same for humans by working to protect the body’s cells and support healthy ageing. Published research and clinical data indicate that resveratrol supports bone health, cardiovascular health, blood glucose levels, healthy cognitive function, skin youthfulness, and oral health. As a powerful antioxidant, resveratrol acts at the cellular level to boost NAD+ by increasing the activity of a key NAD+ synthesising enzyme involved in DNA protection and repair.
Resveratrol has also been shown to penetrate cells and help rejuvenate the mitochondria, again, helping to support healthy ageing. Mitochondria are the powerhouses that create energy inside every cell in our bodies. However, as we age, the mitochondrial function slowly impairs. This leads to the decline of many systems in our body as we get older, including cardiovascular, cognitive, skin, and bone systems. Resveratrol helps reverse or slow this process.
Part of the healthy ageing benefits of resveratrol can be explained by the activation of sirtuins, including SIRT1–7, a family of deacylases that play a critical role in DNA repair, and rely on NAD+ for their function. They possess remarkable capabilities to prevent diseases and even reverse or slow down certain aspects of aging. Resveratrol activates a specific sirtuin-coding gene called SIRT1 which results in gene expression and metabolic pathway activation, both of which are excellent for your energy levels and overall health.
Resveratrol Dosage
The dosage for Resveratrol depends on the person and what it is being used for. Based on studies and clinical trials, it is thought to be safe in doses up to 1500 milligrams daily. We recommend starting at a daily does of 500 mg for the first 4 weeks and if desired, build up to a maximum daily dose of 1000 mg.
As is the case with all supplements, it is wise to start with the lowest possible effective dose and build gradually as needed.
Further Reading
With over 10 years of clinical studies behind the benefits of Resveratrol, there’s an abundance of information to read. Much of the recent studies have now been focused on the benefits of Resveratrol supplementation regarding the management of cognitive decline and Alzheimer's. (please check out our “About” page for further study links)
Below is a link for a clinical human study that encompasses many of the health benefits.
Health Effects of Resveratrol: Results from Human Intervention Trials
What is Alpha-tocopherol
Alpha-tocopherol, one of the eight isoforms of vitamin E, is the most potent fat-soluble antioxidant known in nature. In recent years, the many roles of Alpha-tocopherol have been uncovered, and includes not only antioxidant functions, but also pro-oxidant, cell signaling and gene regulatory functions. Decades of clinical and pre-clinical studies have broadened our understanding of the antioxidant Alpha-tocopherol and its utility in a number of chronic, oxidative stress-induced pathologies.
In addition to its antioxidant function, Alpha-tocopherol has been shown to have other effects on cellular processes, namely on the immune system, proliferation and apoptosis, which makes it an interesting candidate for the study of its anti-cancer properties.
Let’s Take a Closer Look
Though vitamin E is often thought of as a single compound, it’s actually a group of eight fat-soluble compounds with powerful antioxidant effects. Of these eight chemical forms, Alpha-tocopherol best meets the dietary requirements of humans.
Your body uses Alpha-tocopherol for multiple purposes, including protecting you from oxidative stress and supporting your immune system. Alpha-tocopherol exists naturally in certain foods, including seeds, nuts, some vegetables, and some fortified products. You can also take it as a dietary supplement. It plays many roles in your body, and best known for its antioxidant effects, protecting your cells from oxidative damage by neutralizing harmful molecules called free radicals. In addition, it’s needed for proper immune function and cellular signaling. That’s why it’s not surprising that research suggests taking Alpha-tocopherol supplements may benefit your health in several ways, such as skin health, regulating the antioxidant defense system, lower blood pressure, decreased blood lipid levels, cognitive health and menstrual pain.
Because Alpha-tocopherol acts as a powerful antioxidant in the body, studies have shown that supplementing with high doses of it can reduce markers of oxidative stress and boost antioxidant defenses. For example, a recent study of 54 people with diabetic nephropathy (kidney damage caused by high blood sugar) found that supplementing with 350 mg of Alpha-tocopherol per day for 12 weeks significantly increased levels of glutathione peroxidase (GPx) compared with a placebo. GPx is a group of antioxidant enzymes that protect your cells from oxidative damage. A future 2021 study also showed that supplementing with a combination of Alpha-tocopherol and vitamin C daily for 8 weeks reduced markers of oxidative stress, such as malondialdehyde and ROS, in women with endometriosis. Alpha-tocopherol antioxidant properties primarily reacts with reactive oxygen species. In addition, Alpha-tocopherol can also absorb the energy from ultraviolet (UV) light. Thus, it plays important roles in photo-protection, preventing UV-induced free radical damage to skin, along with related anti-inflammatory roles leading to Alpha-tocopherol being used successfully in treating chronic inflammatory skin conditions.
Alpha-tocopherol Dosage
According to the National Institutes of Health (NIH), the tolerable upper Intake Level for supplemental Alpha-tocopherol/vitamin E is currently set at 1,000 mg per day. Unless you have a serve Vitamin E deficiency, this upper limit would not be beneficial.
When used as a daily supplement, a recommended dose of 150 mg - 300 mg has been deemed a well tolerated and beneficial dose.
As is the case with all supplements, it is wise to start with the lowest possible effective dose and build gradually as needed.
Further Reading
There are plenty of clinical studies regarding Alpha-tocopherol and its many benefits (please check out our “About” page for further study links)
Below is a link for the most recent clinical study to date.
Vitamin E and Multiple Health Outcomes (July 2023)
What is Hyaluronic Acid
The body naturally produces hyaluronic acid, which helps lubricate our tissues. It plays a role in skin health, wound healing, bone strength, and improve many other bodily systems and functions
Hyaluronic acid, also known as hyaluronan, is a clear, gooey substance that is naturally produced by your body, with largest amounts of it found in your skin, connective tissue, and eyes. Its main function is to retain water to keep your tissues lubricated and moist, has a variety of uses. Many people take it as a supplement, but it’s also used in topical serums, eye drops, and injections.
Hyaluronic acid supplements can be safely taken by most people and provide many health benefits. Hyaluronic acid is well known for its skin benefits, especially alleviating dry skin, reducing the appearance of fine lines and wrinkles, and speeding up wound healing. It can also help relieve joint pain in people with osteoarthritis.
Let’s Take a Closer Look
Hyaluronic acid is a humectant a substance that retains moisture and it is capable of binding over one thousand times its weight in water. This substance is naturally found in many areas of the human body, including the skin, eyes, and synovial fluid of the joints, Scientific studies have also shown that Hyaluronic Acid helps improve the production of collagen, fight free radicals, maintain skin elasticity, and even has antibacterial and anti-inflammatory properties that help with wound healing.
The average human body contains about 15 grams of Hyaluronic Acid, however, one-third of that gets degraded and synthesised on a daily basis. As we age, the production of key substances in the skin, including hyaluronic acid (along with collagen and elastin) decreases. As a result, our skin loses volume, hydration, and plumpness. It’s naturally present in the skin, but its concentrations increase when there is damage in need of repair. Hyaluronic acid helps wounds heal faster by regulating inflammation levels and signaling the body to build more blood vessels in the damaged area.
Hyaluronic acid is also found in the joints, where it keeps the space between your bones lubricated. When the joints are lubricated, the bones are less likely to grind against each other and cause uncomfortable pain. New research has also begun to investigate the effects of Hyaluronic acid supplements on bone health.
Two studies have found that Hyaluronic acid supplements can help slow the rate of bone loss with osteopenia, the beginning stage of bone loss that precedes osteoporosis. Some older test-tube studies have also shown that high doses of Hyaluronic acid can increase the activity of osteoblasts, the cells responsible for building new bone tissue. This research is ongoing, but is showing promising results so far.
Hyaluronic acid Dosage
When used as a daily supplement, a recommended dose of 150 mg - 300 mg has been deemed a well tolerated and beneficial dose.
As is the case with all supplements, it is wise to start with the lowest possible effective dose and build gradually as needed.
Further Reading
There are plenty of clinical studies regarding Hyaluronic acid and its many benefits (please check out our “About” page for further study links)
Below is a link for the most recent clinical human study to date.
Oral administration of hyaluronic acid to improve skin conditions (Nov 2023)
What is Magnesium Glycinate
Our bodies naturally contain magnesium, but factors like medication interactions, soil depletion, and diets filled with nutrient-poor processed foods mean that some of us aren't getting enough of it. Signs of a deficiency include fatigue, chronic inflammation, unsteady blood sugar, muscle cramping, as well as mood swings, headaches, and an irregular heartbeat. If you suspect you have a magnesium deficiency, your Health Professional can test you via a serum magnesium blood test or a urinary magnesium excretion test.
Let’s Take a Closer Look
Magnesium is an essential element whose benefits are wide-ranging. Magnesium is essential for hundreds of biochemical reactions in the body, it is required as a cofactor for over 300 enzymatic reactions, necessary for protein synthesis, nerve function, muscle contraction, ATP metabolism, synthesis of DNA and RNA. Magnesium is necessary for maintaining a normal heartbeat, normal blood pressure, normal blood sugar levels. Magnesium is required in the transportation of calcium and potassium ions across cell membranes and is a vital element to support our immune system.
Magnesium glycinate is both an essential mineral and electrolyte. It’s involved in the regulation of cellular stress and activity, which means people experiencing lots of stress may benefit from supplementation.
Magnesium glycinate is one type of magnesium supplement that is available to increase levels in people who can use more magnesium, including those with anxiety, diabetes, heart issues and pain. Magnesium glycinate is formed by combining elemental magnesium with the amino acid glycine. This form of magnesium is highly bioavailable, meaning the magnesium is easily absorbed through your small intestine, generally well-tolerated and unlikely to cause loose stools (diarrhea).
The absorption rate and bioavailability of magnesium supplements differ depending on the kind. Usually types that are chelated and those that dissolve in liquid are better absorbed in the gut than less soluble forms. Magnesium glycinate is a chelated form, this means it tends to be better utilized by the body than other forms that are excreted more easily.
Magnesium has a close relationship with the immune system, in both specific and nonspecific immune responses. Magnesium acts as a cofactor for a number of immune system reactions, it functions as a cofactor for antibody-dependent cytolysis, macrophage response, immunoglobulin synthesis, and various other reactions. Even with an adequate diet, some people are at increased risk of Magnesium deficiency, including people with digestive disorders, such as celiac disease and chronic diarrhea. Magnesium is also a central part to a healthy heart rhythm because it's involved in transporting other electrolytes, such as calcium and potassium, into cells. Electrolytes are all important for nerve signals and the muscle contractions of a normal heartbeat. Magnesium as a cofactor assists in regulating blood pressure, glycaemic control and lipid peroxidation. It is therefore also critical to the cardiovascular system.
Magnesium Glycinate Dosage
The recommended dietary intake for Magnesium glycinate depends on your age and gender, but a healthy range is about 300–600 mg/day for most adults, and is usually well tolerated and easily absorbed by your body.
Further Reading
There are plenty of clinical studies regarding Magnesium Glycinate and its many benefits (please check out our “About” page for further study links)
Below is a link for the most recent clinical study to date.
A narrative review on the role of magnesium in immune regulation (July 2023)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10375690/
